NeuroPlant Publications
Kramer NJ, Haney MS, Morgens DW, Jovičić A, Couthouis J, Li A, Ousey J, Ma R, Bieri G, Tsui CK, Shi Y, Hertz NT, Tessier-Lavigne M, Ichida JK, Bassik MC, Gitler AD. CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. Nat Genet. 2018;50: 603–612.
Kim MW, Wang W, Sanchez MI, Coukos R, von Zastrow M, Ting AY. Time-gated detection of protein-protein interactions with transcriptional readout. Elife. 2017;6. doi:10.7554/eLife.30233
Schläpfer P, Zhang P, Wang C, Kim T, Banf M, Chae L, Dreher K, Chavali AK, Nilo-Poyanco R, Bernard T, Kahn D, Rhee SY. Genome-wide prediction of metabolic enzymes, pathways, and gene clusters in plants. Plant Physiol. 2017;173, 2041–2059
Han K, Jeng EE, Hess GT, Morgens DW, Li A, Bassik MC. Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions. Nat Biotechnol. 2017;35: 463–474.
Morgens DW, Wainberg M, Boyle EA, Ursu O, Araya CL, Tsui CK, Haney MS, Hess GT, Han K, Jeng EE, Li A, Snyder MP, Greenleaf WJ, Kundaje A, Bassik MC. Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens. Nat Commun. 2017;8: 15178.
Morgens DW, Deans RM, Li A, Bassik MC. Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes. Nat Biotechnol. 2016;34: 634–636.
Deans RM, Morgens DW, OÅNkesli A, Pillay S, Horlbeck MA, Kampmann M, Gilbert LA, Li A, Mateo R, Smith M, Glenn JS, Carette JE, Khosla C, Bassik MC. Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification. Nat Chem Biol. 2016;12: 361–366.
Yang HH, St-Pierre F, Sun X, Ding X, Lin MZ, Clandinin TR. Subcellular imaging of voltage and calcium signals reveals neural processing in vivo. Cell. 2016;166:245-257.
Chae L, Kim T, Nilo-Poyango R, Rhee SY. Genomic signatures of specialized metabolism in plants. Science. 2014;344(6183):510–513.
Lau W, Fischbach MA, Osbourn A, Sattely ES. Key applications of plant metabolic engineering. PLoS Biol. 2014;12:e1001879.
Anarat-Cappillino G, Sattely ES. The chemical logic of plant natural product biosynthesis. Curr. Opin. Plant Biol. 2014;19:51–58.
Gohl DM, Freifeld L, Silies M, Hwa JJ, Horowitz M, Clandinin TR. Large-scale mapping of transposable element insertion sites using digital encoding of sample identity. Genetics. 2014;196:615-623.
Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, et al., Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nat Methods. 2009;6: 443–445.
Ramot D, Johnson BE, Berry TL Jr, Carnell L, Goodman MB. The Parallel Worm Tracker: a platform for measuring average speed and drug-induced paralysis in nematodes. PLoS One. 2008;3: e2208.
Chalasani SH, Chronis N, Tsunozaki M, Gray JM, Ramot D, Goodman MB, Bargmann CI. Dissecting a circuit for olfactory behaviour in Caenorhabditis elegans. Nature. 2007;450: 63–70.
Kim MW, Wang W, Sanchez MI, Coukos R, von Zastrow M, Ting AY. Time-gated detection of protein-protein interactions with transcriptional readout. Elife. 2017;6. doi:10.7554/eLife.30233
Schläpfer P, Zhang P, Wang C, Kim T, Banf M, Chae L, Dreher K, Chavali AK, Nilo-Poyanco R, Bernard T, Kahn D, Rhee SY. Genome-wide prediction of metabolic enzymes, pathways, and gene clusters in plants. Plant Physiol. 2017;173, 2041–2059
Han K, Jeng EE, Hess GT, Morgens DW, Li A, Bassik MC. Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions. Nat Biotechnol. 2017;35: 463–474.
Morgens DW, Wainberg M, Boyle EA, Ursu O, Araya CL, Tsui CK, Haney MS, Hess GT, Han K, Jeng EE, Li A, Snyder MP, Greenleaf WJ, Kundaje A, Bassik MC. Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens. Nat Commun. 2017;8: 15178.
Morgens DW, Deans RM, Li A, Bassik MC. Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes. Nat Biotechnol. 2016;34: 634–636.
Deans RM, Morgens DW, OÅNkesli A, Pillay S, Horlbeck MA, Kampmann M, Gilbert LA, Li A, Mateo R, Smith M, Glenn JS, Carette JE, Khosla C, Bassik MC. Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification. Nat Chem Biol. 2016;12: 361–366.
Yang HH, St-Pierre F, Sun X, Ding X, Lin MZ, Clandinin TR. Subcellular imaging of voltage and calcium signals reveals neural processing in vivo. Cell. 2016;166:245-257.
Chae L, Kim T, Nilo-Poyango R, Rhee SY. Genomic signatures of specialized metabolism in plants. Science. 2014;344(6183):510–513.
Lau W, Fischbach MA, Osbourn A, Sattely ES. Key applications of plant metabolic engineering. PLoS Biol. 2014;12:e1001879.
Anarat-Cappillino G, Sattely ES. The chemical logic of plant natural product biosynthesis. Curr. Opin. Plant Biol. 2014;19:51–58.
Gohl DM, Freifeld L, Silies M, Hwa JJ, Horowitz M, Clandinin TR. Large-scale mapping of transposable element insertion sites using digital encoding of sample identity. Genetics. 2014;196:615-623.
Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, et al., Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nat Methods. 2009;6: 443–445.
Ramot D, Johnson BE, Berry TL Jr, Carnell L, Goodman MB. The Parallel Worm Tracker: a platform for measuring average speed and drug-induced paralysis in nematodes. PLoS One. 2008;3: e2208.
Chalasani SH, Chronis N, Tsunozaki M, Gray JM, Ramot D, Goodman MB, Bargmann CI. Dissecting a circuit for olfactory behaviour in Caenorhabditis elegans. Nature. 2007;450: 63–70.
